Cyclosporin A-Derivative 1 Free base [286852-20-8]

MedChem Express

Cyclosporin A-Derivative 1 Free base [286852-20-8]

10

286852-20-8

98.81%

C65H117N11O14

1276.69

Cyclosporin A-Derivative 1 (Free base) is a crystalline intermediate derived from the opening of cyclosporin A extracted from patent WO 2013167703 A1. Cyclosporin A is an immunosuppressive agent which can bind to the cyclophilin and inhibit calcineurin.

O=C([C@@](C(C)C)([H])N(C)C([C@H](CC(C)C)N(C)C([C@H](CC(C)C)N(C)C([C@@H](C)NC([C@H](C)NC([C@H](CC(C)C)N(C)C([C@@](C(C)C)([H])NC([C@H](CC(C)C)NC)=O)=O)=O)=O)=O)=O)=O)N(C)[C@]([C@H](OC(C)=O)[C@H](C)C/C=C/C)([H])C(N[C@@H](CC)C(N(C)CC(OC)=O)=O)=O

-20°C,-80°C

12352200