Dabrafenib [1195765-45-7]

MedChem Express

Dabrafenib [1195765-45-7]

10

1195765-45-7

Research Use Only

95%

C23H20F3N5O2S2

519.56

Dabrafenib (GSK2118436A) is an ATP-competitive inhibitor of Raf with IC50s of 5 nM and 0.6 nM for C-Raf and B-RafV600E, respectively.

CC(C)(C)C1=NC(C2=C(F)C(NS(C3=C(F)C=CC=C3F)(=O)=O)=CC=C2)=C(C4=CC=NC(N)=N4)S1

2°C to 8°C,-20°C,-80°C

12352200