Dacomitinib [1110813-31-4]

MedChem Express

Dacomitinib [1110813-31-4]

10

1110813-31-4

Research Use Only

95%

C24H25ClFN5O2

469.94

Dacomitinib (PF-00299804) is a specific and irreversible inhibitor of the ERBB family of kinases with IC50s of 6 nM, 45.7 nM and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively.

O=C(/C=C/CN1CCCCC1)NC2=CC3=C(C=C2OC)N=CN=C3NC4=CC=C(C(Cl)=C4)F

2°C to 8°C,-20°C,-80°C

12352200