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DC0-NH2 [615538-51-7]

HY-129379
MedChem Express
CAS Number615538-51-7
Product group Chemicals
Estimated Purity95%
Molecular Weight550.01
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    DC0-NH2 [615538-51-7]
  • Delivery Days Customer
    10
  • CAS Number
    615538-51-7
  • Estimated Purity
    95%
  • Molecular Formula
    C31H24ClN5O3
  • Molecular Weight
    550.01
  • Scientific Description
    DC0-NH2 is an effector moiety for ADC and a simplified analog of DC1 with better stability. DC0-NH2 is about 1000-fold more cytotoxic than commonly used anticancer agents (ex. Doxorubicin). DC0-NH2 can bind to the minor groove of DNA, followed by alkylation of adenine residues by its propabenzindole (CBI) component.
  • SMILES
    O=C(C(N1)=CC2=C1C=CC(N)=C2)NC3=CC4=C(NC(C(N5C[C@@H](CCl)C6=C5C=C(O)C7=CC=CC=C67)=O)=C4)C=C3
  • Storage Instruction
    -20°C,-80°C
  • UNSPSC
    12352200