Bio-Connect

Ripretinib [1442472-39-0]

HY-112306
MedChem Express
CAS Number1442472-39-0
Product group Chemicals
Estimated Purity98.05%
Molecular Weight510.36
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Ripretinib [1442472-39-0]
  • Delivery Days Customer
    10
  • CAS Number
    1442472-39-0
  • Estimated Purity
    98.05%
  • Molecular Formula
    C24H21BrFN5O2
  • Molecular Weight
    510.36
  • Scientific Description
    Ripretinib (DCC-2618) is an orally bioavailable, selective KIT and PDGFRA switch-control inhibitor. Ripretinib (DCC-2618) targets and binds to both wild-type and mutant forms of KIT and PDGFRA specifically at their switch pocket binding sites, thereby preventing the switch from inactive to active conformations of these kinases and inactivating their wild-type and mutant forms. Ripretinib (DCC-2618) also inhibits multiple other kinase targets, such as FLT3 and KDR (or VEGFR-2). DCC-2618 exerts antineoplastic effect and induces apoptosis.
  • SMILES
    O=C(NC1=CC(C2=CC3=C(C=C(NC)N=C3)N(CC)C2=O)=C(Br)C=C1F)NC4=CC=CC=C4
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200