Deguelin [522-17-8]
HY-13425
Overview
- SupplierMedChem Express
- Product NameDeguelin [522-17-8]
- Delivery Days Customer10
- CAS Number522-17-8
- CertificationResearch Use Only
- Estimated Purity98%
- Molecular FormulaC23H22O6
- Molecular Weight394.42
- Scientific DescriptionDeguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-kappaB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1alpha, COX-2, and NF-kappaB.
- SMILESO=C1[C@]2([H])[C@](COC3=CC(OC)=C(OC)C=C32)([H])OC4=C5C=CC(C)(C)OC5=CC=C14
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200