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Deguelin [522-17-8]

Research Use Only
HY-13425
MedChem Express
CAS Number522-17-8
Product group Chemicals
Estimated Purity98%
Molecular Weight394.42
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Deguelin [522-17-8]
  • Delivery Days Customer
    10
  • CAS Number
    522-17-8
  • Certification
    Research Use Only
  • Estimated Purity
    98%
  • Molecular Formula
    C23H22O6
  • Molecular Weight
    394.42
  • Scientific Description
    Deguelin, a naturally occurring rotenoid, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-kappaB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1alpha, COX-2, and NF-kappaB.
  • SMILES
    O=C1[C@]2([H])[C@](COC3=CC(OC)=C(OC)C=C32)([H])OC4=C5C=CC(C)(C)OC5=CC=C14
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200