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DLK-IN-1 [1620574-24-4]

HY-114331
MedChem Express
CAS Number1620574-24-4
Product group Chemicals
Estimated Purity99.41%
Molecular Weight423.43
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    DLK-IN-1 [1620574-24-4]
  • Delivery Days Customer
    10
  • CAS Number
    1620574-24-4
  • Estimated Purity
    99.41%
  • Molecular Formula
    C20H24F3N5O2
  • Molecular Weight
    423.43
  • Scientific Description
    DLK-IN-1 is a selective, orally active inhibitor of dual leucine zipper kinase (DLK, MAP3K12), with a Ki of 3 nM. DLK-IN-1 retains excellent CNS penetration and is well tolerated following multiple days of dosing at concentrations that exceed those required for DLK inhibition in the brain. DLK-IN-1 has activity in a model of Alzheimers Disease.
  • SMILES
    CC(N1C([C@@H]2[C@]3([H])[C@@]2([H])CN(C4COC4)C3)=CC(C5=CN=C(N)C(OC(F)(F)F)=C5)=N1)C
  • Storage Instruction
    -20°C,-80°C
  • UNSPSC
    12352200