DMOG [89464-63-1]

MedChem Express

DMOG [89464-63-1]

10

89464-63-1

Research Use Only

98%

C6H9NO5

175.14

DMOG (Dimethyloxallyl Glycine) is a cell permeable and competitive inhibitor of HIF-PH, which results in HIF-1alpha stabilisation and accmulation in vitro and in vivo. DMOG is an alpha-ketoglutarate analogue and inhibits alpha-KG-dependent hydroxylases. DMOG acts as a pro-angiogenic agent and plays a protective role in experimental model of colitis and diarrhoea via HIF-1 related signal. DMOG induces cell autophagy.

O=C(OC)CNC(C(OC)=O)=O

2°C to 8°C,-20°C,-80°C

12352200