Docetaxel [114977-28-5]
HY-B0011
Overview
- SupplierMedChem Express
- Product NameDocetaxel [114977-28-5]
- Delivery Days Customer10
- CAS Number114977-28-5
- CertificationResearch Use Only
- Estimated Purity0.96
- Molecular FormulaC43H53NO14
- Molecular Weight807.88
- Scientific DescriptionDocetaxel (RP-56976) is a microtubule depolymerization inhibitor, with an IC50 of 0.2 microM. Docetaxel attenuates the effects of bcl-2 and bcl-xL gene expression. Docetaxel arrests the cell cycle at G2/M and leads to cell apoptosis. Docetaxel has anti-cancer activity.
- SMILESO=C(OC(C)(C)C)N[C@@H](C1=CC=CC=C1)[C@H](C(O[C@@H]2C(C)=C([C@@H](O)C([C@@]3(C)[C@]([C@@](CO4)(OC(C)=O)[C@@]4([H])C[C@@H]3O)([H])[C@@H]5OC(C6=CC=CC=C6)=O)=O)C(C)(C)[C@@]5(O)C2)=O)O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200