Dolutegravir [1051375-16-6]
HY-13238
CAS Number1051375-16-6
Product group Chemicals
Estimated Purity98.76%
Molecular Weight419.38
Overview
- SupplierMedChem Express
- Product NameDolutegravir [1051375-16-6]
- Delivery Days Customer10
- CAS Number1051375-16-6
- CertificationResearch Use Only
- Estimated Purity98.76%
- Molecular FormulaC20H19F2N3O5
- Molecular Weight419.38
- Scientific DescriptionDolutegravir (S/GSK1349572) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir (S/GSK1349572) inhibits HIV-1 viral replication with an IC50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC50=3.6-5.8 nM).
- SMILESFC1=CC(F)=C(C=C1)CNC(C2=CN(C3=C(C2=O)O)C[C@@]([H])(N4C3=O)OCC[C@H]4C)=O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200