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Doramapimod [285983-48-4]

Research Use Only
HY-10320
MedChem Express
CAS Number285983-48-4
Product group Chemicals
Estimated Purity98.01%
Molecular Weight527.66
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Doramapimod [285983-48-4]
  • Delivery Days Customer
    10
  • CAS Number
    285983-48-4
  • Certification
    Research Use Only
  • Estimated Purity
    98.01%
  • Molecular Formula
    C31H37N5O3
  • Molecular Weight
    527.66
  • Scientific Description
    Doramapimod (BIRB 796) is an orally active, highly potent p38 MAPK inhibitor, which has an IC50 for p38alpha=38 nM, for p38beta=65 nM, for p38gamma=200 nM, and for p38delta=520 nM. Doramapimod has picomolar affinity for p38 kinase (Kd=0.1 nM). Doramapimod also inhibits B-Raf with an IC50 of 83 nM.
  • SMILES
    O=C(NC1=CC(C(C)(C)C)=NN1C2=CC=C(C)C=C2)NC3=C4C=CC=CC4=C(OCCN5CCOCC5)C=C3
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200