Doravirine [1338225-97-0]

MedChem Express

Doravirine [1338225-97-0]

10

1338225-97-0

Research Use Only

98%

C17H11ClF3N5O3

425.75

Doravirine (MK-1439) is a highly specific HIV-1 nonnucleoside reverse transcriptase inhibitor with IC50s of 4.5 nM, 5.5 nM and 6.1 nM against the wild type and K103N and Y181C reverse transcriptase mutants, respectively.

N#CC1=CC(OC2=C(C(F)(F)F)C=CN(CC(N3C)=NNC3=O)C2=O)=CC(Cl)=C1

2°C to 8°C,-20°C,-80°C

12352200