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Dovitinib (TKI-258) [405169-16-6]

Research Use Only
S1018
Selleck Chemicals
Product group Chemicals
Price on request
Packing Size
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    Dovitinib (TKI-258) [405169-16-6]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Scientific Description
    Dovitinib (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGF-1R and HER2 in cell-free assays. Phase 4.
  • UNSPSC
    12352200