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Doxorubicin hydrochloride [25316-40-9]

Research Use Only
HY-15142
MedChem Express
CAS Number25316-40-9
Product group Chemicals
Estimated Purity95%
Molecular Weight579.98
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Doxorubicin hydrochloride [25316-40-9]
  • Delivery Days Customer
    10
  • CAS Number
    25316-40-9
  • Certification
    Research Use Only
  • Estimated Purity
    95%
  • Molecular Formula
    C27H30ClNO11
  • Molecular Weight
    579.98
  • Scientific Description
    Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 microM and 2.67 microM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy.
  • SMILES
    COC1=C2C(C(C(C(O)=C(C[C@](C(CO)=O)(O)C[C@@H]3O[C@@]4([H])C[C@H](N)[C@H](O)[C@H](C)O4)C3=C5O)=C5C2=O)=O)=CC=C1.[H]Cl
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200