Stenoparib [1140964-99-3]

MedChem Express

Stenoparib [1140964-99-3]

10

1140964-99-3

Research Use Only

98%

C18H15N5O

317.34

Stenoparib (E7449) is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2, with IC50s of 2.0, 1.0, ~50 and ~50 nM for PARP1, PARP2, TNKS1 and TNKS2, respectively, using 32P-NAD+ as substrate.

O=C1NNC2=C3C1=CC=CC3=NC(CN4CC5=C(C=CC=C5)C4)=N2

2°C to 8°C,-20°C,-80°C

12352200