Bio-Connect

EAI045 [1942114-09-1]

HY-100213
MedChem Express
CAS Number1942114-09-1
Product group Chemicals
Estimated Purity96.53%
Molecular Weight383.4
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    EAI045 [1942114-09-1]
  • Delivery Days Customer
    10
  • CAS Number
    1942114-09-1
  • Estimated Purity
    96.53%
  • Molecular Formula
    C19H14FN3O3S
  • Molecular Weight
    383.4
  • Scientific Description
    EAI045 is an allosteric and the fourth-generation inhibitor of mutant EGFR with IC50s of 1.9, 0.019, 0.19 and 0.002 microM for EGFR, EGFRL858R, EGFRT790M and EGFRL858R/T790M at 10 microM ATP, respectively.
  • SMILES
    O=C(C(C1=C(O)C=CC(F)=C1)N2C(C(C=CC=C3)=C3C2)=O)NC4=NC=CS4
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200