EED226 [2083627-02-3]
HY-101117
CAS Number2083627-02-3
Product group Chemicals
Estimated Purity98.61%
Molecular Weight369.4
Overview
- SupplierMedChem Express
- Product NameEED226 [2083627-02-3]
- Delivery Days Customer10
- CAS Number2083627-02-3
- Estimated Purity98.61%
- Molecular FormulaC17H15N5O3S
- Molecular Weight369.4
- Scientific DescriptionEED226 is a polycomb repressive complex 2 (PRC2) inhibitor, which binds to the K27me3-pocket on embryonic ectoderm development (EED) and shows strong antitumor activity in xenograft mice model. EED226 is a potent, selective, and orally bioavailable EED inhibitor. EED226 inhibits PRC2 with an IC50 of 23.4 nM when the H3K27me0 peptide is used as a substrate in the in vitro enzymatic assays.
- SMILESO=S(C1=CC=C(C2=CN=C(NCC3=CC=CO3)N4C2=NN=C4)C=C1)(C)=O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200