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Eleclazine hydrochloride [1448754-43-5]

HY-16738A
MedChem Express
CAS Number1448754-43-5
Product group Chemicals
Estimated Purity99.27%
Molecular Weight451.83
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Eleclazine hydrochloride [1448754-43-5]
  • Delivery Days Customer
    10
  • CAS Number
    1448754-43-5
  • Estimated Purity
    99.27%
  • Molecular Formula
    C21H17ClF3N3O3
  • Molecular Weight
    451.83
  • Scientific Description
    Eleclazine (GS 6615) hydrochloride is a selective cardiac late sodium current inhibitor and a weak inhibitor of potassium current with IC50 value of <1 microM and approximately 14.2 microM, respectively. Eleclazine hydrochloride shows concurrent protection against autonomically induced atrial premature beats, repolarization alternans and heterogeneity, and atrial fibrillation in porcine model. Eleclazine hydrochloride can be used to research cardiac arrhythmias.
  • SMILES
    O=C1N(CC2=NC=CC=N2)CCOC3=CC=C(C4=CC=C(OC(F)(F)F)C=C4)C=C13.[H]Cl
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200