Enoxacin hydrate [84294-96-2]

MedChem Express

Enoxacin hydrate [84294-96-2]

10

84294-96-2

95.08%

C15H17FN4O3.3/2H2O

347.34

Enoxacin hydrate (Enoxacin sesquihydrate), a fluoroquinolone, interferes with DNA replication and inhibits bacterial DNA gyrase (IC50=126 microg/ml) and topoisomerase IV (IC50=26.5 microg/ml). Enoxacin hydrate is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs. Enoxacin hydrate has potent activities against gram-positive and -negative bacteria. Enoxacin hydrate is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing.

O=C(C1=CN(CC)C2=C(C=C(F)C(N3CCNCC3)=N2)C1=O)O.[1.5H2O]

2°C to 8°C,-20°C,-80°C

12352200