Ertugliflozin L-pyroglutamic acid [1210344-83-4]

MedChem Express

Ertugliflozin L-pyroglutamic acid [1210344-83-4]

10

1210344-83-4

99.77%

C27H32ClNO10

566.0

Ertugliflozin L-pyroglutamic acid (PF-04971729 L-pyroglutamic acid) is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2), with an IC50 of 0.877 nM for h-SGLT2. Has the potential for the treatment of type 2 diabetes mellitus.

ClC1=CC=C([C@]23O[C@@](CO)(CO3)[C@@H](O)[C@H](O)[C@H]2O)C=C1CC4=CC=C(OCC)C=C4.O=C5CC[C@@H](C(O)=O)N5

2°C to 8°C,-20°C,-80°C

12352200