Exo-spin 96

Catalog number: EX07-96
Brand: Cell Guidance Systems
Packing: 96 wells
Price: On Request
Expected delivery time: 7 days
Exo-spin™ 96 column plate

Product specifications for - Exo-spin 96

Product group: Chemicals
Category: Buffers
Datasheet: Datasheet
UNSPSC: 12161700
Scientific information: 
Scientific info: Exo-spin™ 96 provides proven size exclusion chromatography (SEC) mini-column (EX01) technology in a 96-well format, allowing up to 96 individual samples to be processed in less than 30 minutes. Sample volumes up to 0.5 ml can be purified. 

The kit provides flexibility with 8-column strips detachable from the plate, so you can process 8 samples in 8-column strips if needed.

The Exo-spin™ 96 well product offers:
  • High-throughput exosome isolation at the benchtop in the standard 96 well format in under 30 minutes
  • Purify up to 0.5 ml of each sample
  • >97% of free proteins removed
  • Outstanding reproducibility +/- 5% Standard deviation, for consistent exosome purification, time after time
  • Flexibility to just work with single strips of 8 columns at a time
  • The convenience of purified exosomes eluted directly into a 96 well plate ready for high throughput downstream applications
The Exo-spin™ 96 can be used to isolate exosomes directly from protein-rich samples such as sera and plasma. If required, you can concentrate the sample with your preferred concentration method (e.g. concentrator, precipitation buffer)  to isolate from large volumes of low-protein biofluids, such as cell culture medium, cerebral spinal fluid (CSF), and urine.

The EX07 Exo-spin™ kit has been developed to process up to 500 µl blood samples (plasma or sera using iterative loading.
Sheller-Miller S, Trivedi J, Yellon SM, Menon R. Exosomes cause preterm birth in mice: evidence for paracrine signaling in pregnancy. Sci Rep. 2019;9(1):608. Read more
Soares Martins T, Catita J, Martins Rosa I, A B da Cruz E Silva O, Henriques AG. Exosome isolation from distinct biofluids using precipitation and column-based approaches. PLoS One. 2018;13(6):e0198820. Read more
Wang L, Wang C, Jia X, Yu J. Circulating exosomal mir-17 inhibits the induction of regulatory t cells via suppressing tgfbr ii expression in rheumatoid arthritis. Cell Physiol Biochem. 2018;50(5):1754-1763. Read more
Emanueli C, Shearn AIU, Laftah A, et al. Coronary artery-bypass-graft surgery increases the plasma concentration of exosomes carrying a cargo of cardiac micrornas: an example of exosome trafficking out of the human heart with potential for cardiac biomarker discovery. PLoS One. 2016;11(4):e0154274. Read more
de Menezes-Neto A, Sáez MJF, Lozano-Ramos I, et al. Size-exclusion chromatography as a stand-alone methodology identifies novel markers in mass spectrometry analyses of plasma-derived vesicles from healthy individuals. J Extracell Vesicles. 2015;4:27378. Read more