Fiboflapon [936350-00-4]

MedChem Express

Fiboflapon [936350-00-4]

10

936350-00-4

Research Use Only

98.54%

C38H43N3O4S

637.83

Fiboflapon (GSK2190915; AM-803) is a potent and orally bioavailable 5-lipoxygenase-activating protein (FLAP) inhibitor with a potency of 2.9 nM in FLAP binding, an IC50 of 76 nM for inhibition of LTB4 in human blood.

CC(C(O)=O)(C)CC1=C(SC(C)(C)C)C2=CC(OCC3=CC=C(C)C=N3)=CC=C2N1CC4=CC=C(C5=CN=C(OCC)C=C5)C=C4

2°C to 8°C,-20°C,-80°C

12352200