Fingolimod hydrochloride [162359-56-0]

MedChem Express

Fingolimod hydrochloride [162359-56-0]

10

162359-56-0

Research Use Only

95%

C19H34ClNO2

343.93

Fingolimod hydrochloride (FTY720), an analog of sphingosine, is a potent sphingosine 1-phosphate (S1P) receptors modulator. Fingolimod hydrochloride is phosphorylated by sphingosine kinases, particularly by SK2, and then binds S1PR1, 3, 4, and 5. Fingolimod hydrochloride induces the internalization of S1P1, and consequently, inhibits S1P activity. Fingolimod hydrochloride also is a pak1 activator.

OCC(N)(CO)CCC1=CC=C(C=C1)CCCCCCCC.[H]Cl

2°C to 8°C,-20°C,-80°C

12352200