Flumatinib [895519-90-1]

MedChem Express

Flumatinib [895519-90-1]

10

895519-90-1

Research Use Only

98.1%

C29H29F3N8O

562.59

Flumatinib (HHGV678) is an orally available, selective inhibitor of Bcr-Abl. Flumatinib inhibits c-Abl, PDGFRbeta and c-Kit with IC50s of 1.2 nM, 307.6 nM and 665.5 nM, respectively.

O=C(NC1=CC(NC2=NC=CC(C3=CC=CN=C3)=N2)=C(C)N=C1)C4=CC=C(CN5CCN(C)CC5)C(C(F)(F)F)=C4

2°C to 8°C,-20°C,-80°C

12352200