Flumatinib mesylate [895519-91-2]
HY-13905
CAS Number895519-91-2
Product group Chemicals
Estimated Purity98.89%
Molecular Weight658.69
Overview
- SupplierMedChem Express
- Product NameFlumatinib mesylate [895519-91-2]
- Delivery Days Customer10
- CAS Number895519-91-2
- CertificationResearch Use Only
- Estimated Purity98.89%
- Molecular FormulaC30H33F3N8O4S
- Molecular Weight658.69
- Scientific DescriptionFlumatinib (HHGV678) mesylate is an orally active and selective inhibitor of Bcr-Abl. Flumatinib mesylate inhibits c-Abl, PDGFRbeta and c-Kit with IC50 values of 1.2, 307.6 and 665.5 nM, respectively. Flumatinib mesylate inhibits Bcr-Abl autophosphorylation and Stat5 and Erk1/2 phosphorylation. Flumatinib mesylate inhibits tumor growth in chronic myelogenous leukemia model.
- SMILESO=C(NC1=CC(NC2=NC=CC(C3=CC=CN=C3)=N2)=C(C)N=C1)C4=CC=C(CN5CCN(C)CC5)C(C(F)(F)F)=C4.CS(=O)(O)=O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200