Fosphenytoin disodium [92134-98-0]

Catalog number: HY-B1657A_10mM
Brand: MedChem Express
Packing: 10 mM
Other sizes: 5 mg
10 mg
25 mg
50 mg
100 mg
Price: € 95.00
Expected delivery time: 10 days

Product specifications for - Fosphenytoin disodium [92134-98-0]

Product group: Chemicals
Category: Other
CAS No.: 92134-98-0
Purity: >98%
Molecular Formula: C16H13N2Na2O6P
Molecular weight: 406.24
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352200
Scientific information: 
Scientific info: Fosphenytoin sodium is a phenytoin prodrug with similar anticonvulsant properties. In Vivo: Fosphenytoin is an effective neuroprotectant against ischemia-induced damage. In fosphenytoin (30 mg/kg, i.m.)-treated rat 5 min after ischemia episode, hippocampal CA1 pyramidal neurons remain at near control level (13.90 +/- 0.92), however, GFAP staining iss not significantly changed[1]. In fosphenytoin (84 mg/kg)-treated rat, the relative bioavailability of fosphenytoin is 83%. In fully kindled female Wistar rats, fosphenytoin dose-dependently increases the focal seizure (afterdischarge) threshold. Seizure severity and duration at threshold are reduced only after the highest does of fosphenytoin tested (84 mg/kg)[2].
Safety information: