Framycetin [119-04-0]

MedChem Express

Framycetin [119-04-0]

10

119-04-0

Research Use Only

C23H46N6O13

614.64

Framycetin (Neomycin B), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 microM. Framycetin competes for specific divalent metal ion binding sites in RNase P RNA. Framycetin inhibits hammerhead ribozyme with a Ki of 13.5 microM. Framycetin, a 5-azido neomycin B precursor, binds the Drosha site in miR-525 and is used for hepatic encephalopathy and enteropathogenic E. coli infections.

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-20°C

12352200