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Chemical Structure
Chemical Structure
Chemical Structure

FURA 2-AM [108964-32-5]

Research Use Only
CDX-F0014
Chemodex
CAS Number108964-32-5
Product group Chemicals
Estimated Purity>95%
Molecular Weight1001.87
Price on request
Packing Size
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Overview

  • Supplier
    Chemodex
  • Product Name
    FURA 2-AM [108964-32-5]
  • Delivery Days Customer
    10
  • CAS Number
    108964-32-5
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Hazard Information
    Non-hazardous
  • Molecular Formula
    C44H47N3O24
  • Molecular Weight
    1001.87
  • Scientific Description
    Chemical. CAS: 108964-32-5. Formula: C44H47N3O24. MW: 1001.87. Synthetic. The fluorescent probe FURA 2/AM is a membrane-permeable derivative of the calcium chelator FURA 2. Inside cells, FURA 2/AM is rapidly hydrolyzed by cytoplasmic esterases to FURA 2, which remains within the cell. Non-invasive, intracellular calcium indicator that is UV light-excitable. Fluorescent Ca2+ indicator, selective for Ca2+ over other divalent cations Mg2+, Zn2+, Fe2+ and Mn2+. FURA 2/AM is used to determine calcium concentrations in many cellular systems, including: cardiac myocytes, vascular smooth muscle cells and medullary collecting tubules. Spectral properties in the presence of low calcium concentrations (lambdaex = 362nm, lambdaem = 512nm) differ from those during high calcium conditions (lambdaex = 335nm, lambdaem = 505nm). FURA 2 is preferred for ratio-imaging microscopy, in which it is more practical to change excitation wavelengths than emission wavelengths. Spectral Data: lambdaex 355nm; lambdaem 495nm in 0.1 M Tris pH 8.0. - The fluorescent probe FURA 2/AM is a membrane-permeable derivative of the calcium chelator FURA 2. Inside cells, FURA 2/AM is rapidly hydrolyzed by cytoplasmic esterases to FURA 2, which remains within the cell. Non-invasive, intracellular calcium indicator that is UV light-excitable. Fluorescent Ca2+ indicator, selective for Ca2+ over other divalent cations Mg2+, Zn2+, Fe2+ and Mn2+. FURA 2/AM is used to determine calcium concentrations in many cellular systems, including: cardiac myocytes, vascular smooth muscle cells and medullary collecting tubules. Spectral properties in the presence of low calcium concentrations (lambdaex = 362nm, lambdaem = 512nm) differ from those during high calcium conditions (lambdaex = 335nm, lambdaem = 505nm). FURA 2 is preferred for ratio-imaging microscopy, in which it is more practical to change excitation wavelengths than emission wavelengths. Spectral Data: lambdaex 355nm; lambdaem 495nm in 0.1 M Tris pH 8.0.
  • SMILES
    O=C(OCOC(C)=O)C1=CN=C(O1)C2=CC3=C(O2)C=C(N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C(OCCOC4=C(N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C=CC(C)=C4)=C3
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200