Denfivontinib [1457983-28-6]

MedChem Express

Denfivontinib [1457983-28-6]

10

1457983-28-6

Research Use Only

95.03%

C25H25BrN6O2

521.41

Denfivontinib (G-749) is a potent, oral active and ATP competitive FLT3 inhibitor, with IC50s of 0.4 nM and 0.6 nM for FLT3 wild type and FLT3-D835Y, respectively. Denfivontinib can be used for the research of agent resistance for acute myeloid leukemia (AML).

O=C1NC=C(C2=C1C(NC3=CC=C(C=C3)OC4=CC=CC=C4)=NC(NC5CCN(CC5)C)=N2)Br

2°C to 8°C,-20°C,-80°C

12352200