Gefitinib (ZD1839) [184475-35-2]
S1025
Overview
- SupplierSelleck Chemicals
- Product NameGefitinib (ZD1839) [184475-35-2]
- Delivery Days Customer9
- CAS Number184475-35-2
- CertificationResearch Use Only
- Scientific DescriptionGefitinib (ZD-1839, Iressa) is an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively. Gefitinib promotes autophagy and apoptosis of lung cancer cells via blockade of the PI3K/AKT/mTOR pathway.
- UNSPSC12352200