Ginsenoside Rd [52705-93-8]

Selleck Chemicals

Ginsenoside Rd [52705-93-8]

9

52705-93-8

Research Use Only

Ginsenoside Rd (Panaxoside Rd, Sanchinoside Rd), a minor ginseng saponin, has several pharmacological activities such as immunosuppressive activity, anti-inflammatory activity, immunological adjuvant, anti-cancer activity and wound-healing activity. Ginsenoside Rd inhibits TNFalfa-induced NF-kappaB transcriptional activity with an IC50 of 12.05±0.82 muM in HepG2 cells. Ginsenoside Rd inhibits expression of COX-2 and iNOS mRNA. Ginsenoside Rd also inhibits Ca2+ influx. Ginsenoside Rd inhibits CYP2D6, CYP1A2, CYP3A4, and CYP2C9, with IC50s of 58.0±4.5 muM, 78.4±5.3 muM, 81.7±2.6 muM, and 85.1±9.1 muM, respectively.

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