Yoda 1 [448947-81-7]

MedChem Express

Yoda 1 [448947-81-7]

10

448947-81-7

Research Use Only

98.28%

C13H8Cl2N4S2

355.27

Yoda 1 is a potent and selective Piezo1 agonist. Yoda 1 activates purified Piezo1 channels. Yoda 1 potently inhibits macropinocytosis induced by epidermal growth factor (EGF). Yoda 1 enhances Ca2+ influx followed by activation of the calcium-activated potassium channel KCa3.1 and inhibition of Rac1 activation.

ClC1=C(CSC2=NN=C(C3=NC=CN=C3)S2)C(Cl)=CC=C1

2°C to 8°C,-20°C,-80°C

12352200