GNE-272 [1936428-93-1]

MedChem Express

GNE-272 [1936428-93-1]

10

1936428-93-1

99.76%

C22H25FN6O2

424.47

GNE-272 is a potent and selective CBP/EP300 inhibitor with IC50 values of 0.02, 0.03 and 13 microM for CBP, EP300 and BRD4, respectively. GNE-272 is also a selective in vivo probe for CBP/EP300.

CC(N1CCC2=C(C(NC3=C(F)C=C(C4=CN(C)N=C4)C=C3)=NN2[C@@H]5COCC5)C1)=O

2°C to 8°C,-20°C,-80°C

12352200