GNF-5837 [1033769-28-6]
HY-13491
Overview
- SupplierMedChem Express
- Product NameGNF-5837 [1033769-28-6]
- Delivery Days Customer10
- CAS Number1033769-28-6
- CertificationResearch Use Only
- Estimated Purity98%
- Molecular FormulaC28H21F4N5O2
- Molecular Weight535.49
- Scientific DescriptionGNF-5837 is a potent, selective, and orally bioavailable pan-tropomyosin receptor kinase (TRK) inhibitor which display antiproliferative effects in cellular Ba/F3 assays ( IC50 values of 7 nM, 9 nM and 11 nM for cells containing the fusion proteins Tel-TrkC, Tel-TrkB and Tel-TrkA, respectively) .
- SMILESO=C(NC1=CC(C(F)(F)F)=CC=C1F)NC2=CC=C(C)C(NC3=CC(NC/4=O)=C(C=C3)C4=C\C5=CC=CN5)=C2
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200