GNF-7 [839706-07-9]
HY-10943
CAS Number839706-07-9
Product group Chemicals
Estimated Purity98.93%
Molecular Weight547.53
Overview
- SupplierMedChem Express
- Product NameGNF-7 [839706-07-9]
- Delivery Days Customer10
- CAS Number839706-07-9
- CertificationResearch Use Only
- Estimated Purity98.93%
- Molecular FormulaC28H24F3N7O2
- Molecular Weight547.53
- Scientific DescriptionGNF-7 is a multikinase inhibitor. GNF-7 is a Bcr-Abl inhibitor, with IC50s of 133 nM and 61 nM for Bcr-AblWT and Bcr-AblT315I, respectively. GNF-7 also possesses inhibitory activity against both ACK1 (activated CDC42 kinase 1) and GCK (germinal center kinase) with IC50s of 25 nM and 8 nM, respectively. GNF-7 can be used for the research of hematologic malignancies.
- SMILESO=C(NC1=CC=C(C)C(N2CC3=CN=C(NC4=CC=C(C)N=C4)N=C3N(C)C2=O)=C1)C5=CC=CC(C(F)(F)F)=C5
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200