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GNF-7 [839706-07-9]

Research Use Only
HY-10943
MedChem Express
CAS Number839706-07-9
Product group Chemicals
Estimated Purity98.93%
Molecular Weight547.53
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    GNF-7 [839706-07-9]
  • Delivery Days Customer
    10
  • CAS Number
    839706-07-9
  • Certification
    Research Use Only
  • Estimated Purity
    98.93%
  • Molecular Formula
    C28H24F3N7O2
  • Molecular Weight
    547.53
  • Scientific Description
    GNF-7 is a multikinase inhibitor. GNF-7 is a Bcr-Abl inhibitor, with IC50s of 133 nM and 61 nM for Bcr-AblWT and Bcr-AblT315I, respectively. GNF-7 also possesses inhibitory activity against both ACK1 (activated CDC42 kinase 1) and GCK (germinal center kinase) with IC50s of 25 nM and 8 nM, respectively. GNF-7 can be used for the research of hematologic malignancies.
  • SMILES
    O=C(NC1=CC=C(C)C(N2CC3=CN=C(NC4=CC=C(C)N=C4)N=C3N(C)C2=O)=C1)C5=CC=CC(C(F)(F)F)=C5
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200