GSK-690693 [937174-76-0]

MedChem Express

GSK-690693 [937174-76-0]

10

937174-76-0

Research Use Only

96.35%

C21H27N7O3

425.48

GSK-690693 is an ATP-competitive pan-Akt inhibitor with IC50s of 2 nM, 13 nM, 9 nM for Akt1, Akt2 and Akt3, respectively. GSK-690693 is also an AMPK inhibitor, affects Unc-51-like autophagy activating kinase 1 (ULK1) activity and robustly inhibits STING-dependent IRF3 activation.

CC(O)(C)C#CC1=NC=C(OC[C@@H]2CNCCC2)C3=C1N=C(C4=NON=C4N)N3CC

2°C to 8°C,-20°C,-80°C

12352200