GSK137647A [349085-82-1]

MedChem Express

GSK137647A [349085-82-1]

10

349085-82-1

Research Use Only

99.88%

C16H19NO3S

305.39

GSK137647A (GSK 137647) is a potent, selective free fatty acid receptor 4 (FFA4) agonist with pEC50 values of 6.3, 6.2, and 6.1 for human, mouse and rat FFA4, and pEC50 values < 4.5 for all three species for FFA1, FFA2, and FFA3, respectively. GSK137647A has anti-inflammatory activity. GSK137647A induces insulin secretion and inhibits epithelial ion transport, GSK137647A is related to regulation of glucose homeostasis and anti-inflammatory response.

O=S(C1=CC=C(OC)C=C1)(NC2=C(C)C=C(C)C=C2C)=O

2°C to 8°C,-20°C,-80°C

12352200