GSK864 [1816331-66-4]

MedChem Express

GSK864 [1816331-66-4]

10

1816331-66-4

99.29%

C30H31FN6O4

558.6

GSK864 is an isocitrate dehydrogenase 1 (IDH1) mutant inhibitor; inhibits IDH1 mutants R132C, R132H, and R132G with IC50 values of 8.8, 15.2 and 16.6 nM.

FC(C=C1)=CC=C1CN2N=C(C(NC3=CC(C)=C(OC)C(C)=C3)=O)C4=C2[C@](C(N)=O)(C)CN(C(C5=CC=CN5)=O)C4

2°C to 8°C,-20°C,-80°C

12352200