GTS-21 dihydrochloride [156223-05-1]

MedChem Express

GTS-21 dihydrochloride [156223-05-1]

10

156223-05-1

Research Use Only

99.65%

C19H22Cl2N2O2

381.3

GTS-21 dihydrochloride is a selective alpha7 nicotinic acetylcholine receptor (alpha7-nAChR) agonist with anti-inflammatory and cognition-enhancing activities. GTS-21 dihydrochloride is also a alpha4beta2 (Ki=20 nM for humanalpha4beta2) and 5-HT3A receptor (IC50=3.1 microM) antagonist.

COC1=CC(OC)=CC=C1/C=C2CCCN=C\2C3=CC=CN=C3.Cl[H].Cl[H]

2°C to 8°C,-20°C,-80°C

12352200