GW2580 [870483-87-7]

MedChem Express

GW2580 [870483-87-7]

10

870483-87-7

Research Use Only

98.45%

C20H22N4O3

366.41

GW2580 is an orally bioavailable and selective inhibitor of c-Fms kinase which completely inhibits human cFMS kinase in vitro at 0.06 microM. GW2580 acts as a competitive inhibitor of ATP binding to the cFMS kinase and inhibits colony-stimulating-factor-1 signaling.

NC1=NC(N)=C(CC2=CC(OC)=C(OCC3=CC=C(OC)C=C3)C=C2)C=N1

2°C to 8°C,-20°C,-80°C

12352200