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GW9508 [885101-89-3]

Research Use Only
HY-15589
MedChem Express
CAS Number885101-89-3
Product group Chemicals
Estimated Purity99.33%
Molecular Weight347.41
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    GW9508 [885101-89-3]
  • Delivery Days Customer
    10
  • CAS Number
    885101-89-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.33%
  • Molecular Formula
    C22H21NO3
  • Molecular Weight
    347.41
  • Scientific Description
    GW9508 is a potent and selective G protein-coupled receptors FFA1 (GPR40) and GPR120 agonist with pEC50s of 7.32 and 5.46, respectively. GW9508 shows ~100-fold selectivity for GPR40 over GPR120. GW9508 is inactive against other GPCRs, kinases, proteases, integrins and PPARs. GW9508 is a glucose-sensitive insulin secretagogue and an ATP-sensitive potassium (KATP) channels opener. Anti-inflammatory and anti-atherosclerotic activities.
  • SMILES
    O=C(O)CCC1=CC=C(NCC2=CC=CC(OC3=CC=CC=C3)=C2)C=C1
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200