HSP27 inhibitor J2 [2133499-85-9]

MedChem Express

HSP27 inhibitor J2 [2133499-85-9]

10

2133499-85-9

99.25%

C13H12O4S

264.3

HSP27 inhibitor J2 (J2) is a HSP27 inhibitor, which significantly induces abnormal HSP27 dimer formation and inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function thereof. HSP27 inhibitor J2 (J2) remarkably enhances the antiproliferative activity of 17-AAG and sensitizes cisplatin-induced lung cancer cell growth inhibition.

O=C1C=C(C)OC2=C1C(O)=CC(OCC3SC3)=C2

2°C to 8°C,-20°C,-80°C

12352200