Idebenone [58186-27-9]

MedChem Express

Idebenone [58186-27-9]

10

58186-27-9

Research Use Only

97.02%

C19H30O5

338.44

Idebenone, a well-appreciated mitochondrial protectant, exhibits protective efficacy against neurotoxicity and can be used for the research of Alzheimers disease, Huntingtons disease. Idebenone (oxidised form) has a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid in astroglial homogenates (IC50=16.65 microM). Idebenone, a coenzyme Q10 analog and an antioxidant, induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells. Idebenone quickly crosses the blood-brain barrier.

O=C1C(CCCCCCCCCCO)=C(C)C(C(OC)=C1OC)=O

2°C to 8°C,-20°C,-80°C

12352200