IDH-889 [1429179-07-6]

Biorbyt

IDH-889 [1429179-07-6]

16

1429179-07-6

Research Use Only

C23H25FN6O2

436.482

IDH889 is a potent and selective inhibitors of IDH1. IDH899 shows IDH (R132H) IC50 = 20 nM; Cell 2-HG IC50 = 14 nM.

FC1C([H])=C([H])C(=C([H])C=1C([H])([H])[H])C1C([H])=NC([C@]([H])(C([H])([H])[H])N([H])C2=NC([H])=C([H])C(=N2)N2C(=O)OC([H])([H])[C@]2([H])C([H])(C([H])([H])[H])C([H])([H])[H])=NC=1[H]

12352200