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Indirubin-3-monoxime [160807-49-8]

Research Use Only
HY-19807
MedChem Express
CAS Number160807-49-8
Product group Chemicals
Estimated Purity99.89%
Molecular Weight277.28
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Indirubin-3-monoxime [160807-49-8]
  • Delivery Days Customer
    10
  • CAS Number
    160807-49-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.89%
  • Molecular Formula
    C16H11N3O2
  • Molecular Weight
    277.28
  • Scientific Description
    Indirubin-3-monoxime is a potent GSK-3beta inhibitor, and weakly inhibits 5-Lipoxygenase, with IC50s of 22 nM and 7.8-10 microM, respectively; Indirubin-3-monoxime also shows inhibitory activities against CDK5/p25 and CDK1/cyclin B, with IC50s of 100 and 180 nM.
  • SMILES
    O=C1NC2=C(C=CC=C2)/C1=C3NC4=C(C=CC=C4)C\3=N/O
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200