IQ-1S free acid [23146-22-7]

MedChem Express

IQ-1S free acid [23146-22-7]

10

23146-22-7

Research Use Only

99.35%

C15H9N3O

247.25

IQ-1S free acid is a prospective inhibitor of NF-kappaB/activating protein 1 (AP-1) activity with an IC50 of 2.3+/-0.41 microM. IQ-1S free acid has binding affinity (Kd values) in the nanomolar range for all three JNKs with Kds of 100 nM, 240 nM, and 360 nM for JNK3, JNK1, and JNK2, respectively.

O/N=C1C2=C(C3=NC4=CC=CC=C4N=C3\1)C=CC=C2

2°C to 8°C,-20°C,-80°C

12352200