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Ivosidenib [1448347-49-6]

Research Use Only
HY-18767
MedChem Express
CAS Number1448347-49-6
Product group Chemicals
Estimated Purity98.63%
Molecular Weight582.96
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Ivosidenib [1448347-49-6]
  • Delivery Days Customer
    10
  • CAS Number
    1448347-49-6
  • Certification
    Research Use Only
  • Estimated Purity
    98.63%
  • Molecular Formula
    C28H22ClF3N6O3
  • Molecular Weight
    582.96
  • Scientific Description
    Ivosidenib (AG-120) is an orally active inhibitor of isocitrate dehydrogenase 1 mutant (mIDH1) enzyme, it exhibits profound d-2-hydroxyglutatrate (2-HG) lowering in vivo. Ivosidenib (AG-120) has the potential for AML therapy due to its acceptable safety profile and clinical activity.
  • SMILES
    ClC1=C([C@H](N(C2=CC(F)=CN=C2)C([C@H]3N(C4=NC=CC(C#N)=C4)C(CC3)=O)=O)C(NC5CC(F)(F)C5)=O)C=CC=C1
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200