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K145 hydrochloride [1449240-68-9]

Research Use Only
HY-15779A
MedChem Express
CAS Number1449240-68-9
Product group Chemicals
Estimated Purity99.34%
Molecular Weight384.92
Price on request
Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    K145 hydrochloride [1449240-68-9]
  • Delivery Days Customer
    10
  • CAS Number
    1449240-68-9
  • Certification
    Research Use Only
  • Estimated Purity
    99.34%
  • Molecular Formula
    C18H25ClN2O3S
  • Molecular Weight
    384.92
  • Scientific Description
    K145 hydrochloride is a selective, substrate-competitive and orally active SphK2 inhibitor with an IC50 of 4.3 microM and a Ki of 6.4 microM. K145 hydrochloride is inactive against SphK1 and other protein kinases. K145 hydrochloride induces cell apoptosis and has potently antitumor activity.
  • SMILES
    O=C(N(CCN)C/1=O)SC1=C/CCC2=CC=C(OCCCC)C=C2.[H]Cl
  • Storage Instruction
    2°C to 8°C,-20°C,-80°C
  • UNSPSC
    12352200