Kartogenin [4727-31-5]

MedChem Express

Kartogenin [4727-31-5]

10

4727-31-5

Research Use Only

95%

C20H15NO3

317.34

Kartogenin (KGN) is an inducer of differentiation of human mesenchymal stem cells into chondrocytes, with an EC50 of 100 nM. Kartogenin binds filamin A, disrupts its interaction with the transcription factor core-binding factor beta subunit (CBFbeta), and induces chondrogenesis by regulating the CBFbeta-RUNX1 transcriptional program. Kartogenin can be used for the research of osteoarthritis (OA).

O=C(O)C1=CC=CC=C1C(NC2=CC=C(C3=CC=CC=C3)C=C2)=O

2°C to 8°C,-20°C,-80°C

12352200