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Chemical Structure
Chemical Structure
Chemical Structure

KBU2046 [1143863-69-7]

Research Use Only
AG-CR1-0159
AdipoGen Life Sciences
CAS Number1143863-69-7
Product group Chemicals
Estimated Purity>98%
Molecular Weight242.2
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Packing Size
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    KBU2046 [1143863-69-7]
  • Delivery Days Customer
    10
  • CAS Number
    1143863-69-7
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Hazard Information
    Non-hazardous
  • Molecular Formula
    C15H11FO2
  • Molecular Weight
    242.2
  • Scientific Description
    Chemical. CAS: 1143863-69-7. Formula: C15H11FO2. MW: 242.2. Highly selective metastasis inhibitor in vitro. Binds to and stabilizes Cdc37-HSP90beta heterocomplexes, consequently blocking its function and inhibiting cancer cell motility. Does not bind to Cdc37 or HSP90beta alone. Inhibits cancer metastasis in vivo in murine models of human prostate and breast cancer. Shown to exhibit a complete lack of cellular cytotoxicity and systemic toxicity. - Highly selective metastasis inhibitor in vitro. Binds to and stabilizes Cdc37-HSP90beta heterocomplexes, consequently blocking its function and inhibiting cancer cell motility. Does not bind to Cdc37 or HSP90beta alone. Inhibits cancer metastasis in vivo in murine models of human prostate and breast cancer. Shown to exhibit a complete lack of cellular cytotoxicity and systemic toxicity.
  • SMILES
    O=C1C(C2=CC=C(F)C=C2)COC3=CC=CC=C31
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352200